Regulated and constitutive protein targeting can be distinguished by secretory polarity in thyroid epithelial cells.
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چکیده
منابع مشابه
Regulated and constitutive protein targeting can be distinguished by secretory polarity in thyroid epithelial cells
We have studied concurrent apical/basolateral and regulated/constitutive secretory targeting in filter-grown thyroid epithelial monolayers in vitro, by following the exocytotic routes of two newly synthesized endogenous secretory proteins, thyroglobulin (Tg) and p500. Tg is a regulated secretory protein as indicated by its acute secretory response to secretagogues. Without stimulation, pulse-la...
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ژورنال
عنوان ژورنال: Journal of Cell Biology
سال: 1991
ISSN: 0021-9525,1540-8140
DOI: 10.1083/jcb.112.3.365